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Case Report 


Efficacy of Modafinil for Dissociative Identity Disorder with Hypersomnia

Adriana Fiszman, Ivan Figueira, Camilla Pinna, Claudia Cecilia Da Silva Rego, Soniza Vieira Alves-leon, Carlos H. Schenck.


Abstract
We report the case of a 22-year-old female victim of childhood sexual abuse with dissociative identity disorder and hypersomnia who remitted from both clinical conditions with the use of modafinil 400 mg/day. We review the literature supporting the sleep-dissociation theory, where trauma-related memories induce a labile sleep-wake cycle allowing dreamlike mentation to intrude into waking consciousness and precipitate dissociative symptoms. The studies examined here found high correlations between dissociation and unusual sleep experiences. This may explain why in our case report modafinil, a medication with wake-promoting properties, improved both excessive daytime sleepiness and dissociation. Future studies are needed to determine which alterations in the sleep-wake cycle are most associated with dissociative disorders. We suggest a new perspective on the use of medications for comorbid hypersomnia, such as modafinil, in the treatment of dissociation.

Key words: Dissociative disorders, excessive daytime sleepiness, sleep disorders, psychopharmacology, childhood sexual abuse


 
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How to Cite this Article
Pubmed Style

Fiszman A, Figueira I, Pinna C, Rego CCDS, Alves-leon SV, Schenck CH. Efficacy of Modafinil for Dissociative Identity Disorder with Hypersomnia. Sleep Hypn. 2020; 22(1): 1-7.

Web Style

Fiszman A, Figueira I, Pinna C, Rego CCDS, Alves-leon SV, Schenck CH. Efficacy of Modafinil for Dissociative Identity Disorder with Hypersomnia. https://www.sleepandhypnosis.com/?mno=130175 [Access: October 13, 2025].

AMA (American Medical Association) Style

Fiszman A, Figueira I, Pinna C, Rego CCDS, Alves-leon SV, Schenck CH. Efficacy of Modafinil for Dissociative Identity Disorder with Hypersomnia. Sleep Hypn. 2020; 22(1): 1-7.


Vancouver/ICMJE Style

Fiszman A, Figueira I, Pinna C, Rego CCDS, Alves-leon SV, Schenck CH. Efficacy of Modafinil for Dissociative Identity Disorder with Hypersomnia. Sleep Hypn. (2020), [cited October 13, 2025]; 22(1): 1-7.


Harvard Style

Fiszman, A., Figueira, . I., Pinna, . C., Rego, . C. C. D. S., Alves-leon, . S. V. & Schenck, . C. H. (2020) Efficacy of Modafinil for Dissociative Identity Disorder with Hypersomnia. Sleep Hypn, 22 (1), 1-7.


Turabian Style

Fiszman, Adriana, Ivan Figueira, Camilla Pinna, Claudia Cecilia Da Silva Rego, Soniza Vieira Alves-leon, and Carlos H. Schenck. 2020. Efficacy of Modafinil for Dissociative Identity Disorder with Hypersomnia. Sleep and Hypnosis, 22 (1), 1-7.


Chicago Style

Fiszman, Adriana, Ivan Figueira, Camilla Pinna, Claudia Cecilia Da Silva Rego, Soniza Vieira Alves-leon, and Carlos H. Schenck. "Efficacy of Modafinil for Dissociative Identity Disorder with Hypersomnia." Sleep and Hypnosis 22 (2020), 1-7.


MLA (The Modern Language Association) Style

Fiszman, Adriana, Ivan Figueira, Camilla Pinna, Claudia Cecilia Da Silva Rego, Soniza Vieira Alves-leon, and Carlos H. Schenck. "Efficacy of Modafinil for Dissociative Identity Disorder with Hypersomnia." Sleep and Hypnosis 22.1 (2020), 1-7. Print.


APA (American Psychological Association) Style

Fiszman, A., Figueira, . I., Pinna, . C., Rego, . C. C. D. S., Alves-leon, . S. V. & Schenck, . C. H. (2020) Efficacy of Modafinil for Dissociative Identity Disorder with Hypersomnia. Sleep and Hypnosis, 22 (1), 1-7.


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